CHSG Members Answer the Call from CNN

A few weeks ago, CHSG was contacted by a reporter from CNN seeking video submissions from patients, describing the experience of cluster headache. Our family did not disappoint! Over a dozen courageous men and women submitted honest, raw, uncensored, unfiltered video of life with cluster headache.  Seven were featured in the October 3rd CNN article. 

Cerebral hemodynamics in the different phases of migraine and cluster headache

Headache is one of the most common ailments; migraine is one of the most prevalent and disabling neurological disorders and cluster headache presents as one of the most excruciating pain disorders. Both are complex disorder characterized by recurrent episodes of headache. A key feature is that various triggers can set off an attack providing the opportunity to explore disease mechanisms by experimentally inducing attacks. This review summarizes neuroimaging and hemodynamic studies in human in provoked and spontaneous attacks of migraine and cluster headache.

Prescribing Oxygen for Cluster Headache: A Guide for the Provider

Oxygen is the standard of care for acute treatment of cluster headache. CMS, the US Centers for Medicaid and Medicare Services, has made the indefensible decision to not cover oxygen for cluster headache for patients with Medicaid and Medicare insurance, despite the evidence and professional guidelines. Commercial insurance generally covers oxygen for cluster headache.

Calcitonin gene-related peptide antagonism and cluster headache: an emerging new treatment

Calcitonin gene-related peptide (CGRP) is a key signaling molecule involved in migraine pathophysiology. Efficacy of CGRP monoclonal antibodies and antagonists in migraine treatment has fueled an increasing interest in the prospect of treating cluster headache (CH) with CGRP antagonism. The exact role of CGRP and its mechanism of action in CH have not been fully clarified. A search for original studies and randomized controlled trials (RCTs) published in English was performed in PubMed and in ClinicalTrials.gov. The search term used was “cluster headache and calcitonin gene related peptide” and “primary headaches and calcitonin gene related peptide.”